West Ham are without Aaron Cresswell through suspension following his controversial red card against Crystal Palace.
Fellow left-back Arthur Masuaku (knee) is still sidelined, along with right-back Sam Byram (hamstring), winger Gokhan Tore (thigh) and strikers Andy Carroll (knee) and Diafra Sakho (back).
But club-record signing Andre Ayew has an outside chance of making the squad after recovering from the thigh injury he suffered on the opening day of the season.
Sunderland defenders Lamine Kone and Patrick van Aanholt are fit as David Moyes' injury problems ease.
Kone missed last weekend's 2-0 defeat at Stoke with a hamstring problem, while Van Aanholt lasted just 40 minutes before having to leave the field with an adductor strain, but both are fit for the trip to the London Stadium.
Goalkeeper Vito Mannone (fractured elbow) and midfielder Sebastian Larsson (knee) are back in light training, while winger Adnan Januzaj is expected to join them next week and Jason Denayer, Jan Kirchhoff and Lee Cattermole are not far behind, leaving striker Fabio Borini (groin) as the only long-term absentee.
West Ham squad: Adrian, Randolph, Spiegel, Arbeloa, Reid, Collins, Ogbonna, Oxford, Kouyate, Obiang, Fernandes, Nordtveit, Noble, Payet, Lanzini, Antonio, Feghouli, Ayew, Zaza, Fletcher, Calleri.
Sunderland squad: Pickford, Mika, Love, Manquillo, Van Aanholt, Kone, Djilobodji, O'Shea, McNair, Rodwell, Gooch, Khazri, Pienaar, Honeyman, Defoe, Asoro, Watmore, Anichebe.